Polyneuropathy (LPN2) – Leonberger
Kodas: H342
Įdėjimo į krepšelį mygtukas pasirodys po to, kai aukščiau pasirinksite reikšmę
Short description
Polyneuropathy is a neural disorder that affects the peripheral nervous system (the nerves outside the spinal cord and brain).
General information
Polyneuropathy is a neural disorder that affects the peripheral nervous system (the nerves outside the spinal cord and brain). This variant of the disease, LPN2, occurs in the Leonberger. It is caused by an incompletely dominant mutation to the gene GJA9.
Specifications
| Breeds | |
|---|---|
| Gene | GJA9 |
| Chromosome | 15 |
| Mutation | c.1107_1108delAG |
| Organ | Nervous System |
| Specimen | Swab, Blood EDTA, Blood Heparin, Semen, Tissue |
| Mode of Inheritance | Autosomal Incomplete Dominant |
| Also known as | LPN2 |
Clinical features
Affected dogs present with weakness, muscle atrophy, difficulty breathing and a change in barking pitch.
References
Pubmed ID: 28841859
Year published: 2017
Omia ID: 2119
Omia variant ID:
Turnaround information
- 10 working days