Hypocatalasia (CAT)
Kodas: H364
Short description
Hypocatalasia (known variously as Acatalasia, Catalasia Deficiency, Hypocatalasemia, Acatalasemia, Takahara’s Disease or CAT) is a disorder in which the body does not produce enough of the enzyme catalase, which can result in ulcers of the mouth.
General information
Hypocatalasia (known variously as Acatalasia, Catalasia Deficiency, Hypocatalasemia, Acatalasemia, Takahara’s Disease or CAT) is a disorder in which the body does not produce enough of the enzyme catalase, which can result in ulcers of the mouth. A semi-dominant mutation causing the disease has been observed in a range of breeds, including the Beagle, American Foxhound and Miniature Poodle.
Specifications
| Breeds | Poodle (Miniature), English Foxhound, Harrier, Treeing Walker Coonhound, American Foxhound, Beagle |
|---|---|
| Gene | CAT |
| Chromosome | 18 |
| Mutation | c.979G>A |
| Organ | Digestive System |
| Specimen | Swab, Blood EDTA, Blood Heparin, Semen, Tissue |
| Mode of Inheritance | Autosomal Incomplete Dominant |
Clinical features
Affected dogs are at increased risk of oral ulcers and resulting complications, including gangrene of the mouth and tooth loss.
References
Pubmed ID: 11137458
Year published: 2000
Omia ID: 1138
Omia variant ID:
Turnaround information
- 10 working days