Von Willebrand Disease Type 3 – Scottish Terrier
Kodas: H744
Short description
VonWillebrand Disease (vWD) is a group of bleeding disorders caused by deficiency in the von Willebrand factor (vWF), which results in poorly functioning blood platelets and can lead to uncontrolled bleeding.
General information
VonWillebrand Disease (vWD) is a group of bleeding disorders caused by deficiency in the von Willebrand factor (vWF), which results in poorly functioning blood platelets and can lead to uncontrolled bleeding. Type III (Type 3) vWD is the most severe form of the disease, and is caused by a recessive mutation to the gene vWF. This variant of Type III vWD is found in the Scottish Terrier. Related variants are also found in the Shetland Sheepdog and Dutch Kooiker.
Specifications
| Breeds | |
|---|---|
| Gene | VWF |
| Chromosome | 27 |
| Mutation | c.255delC |
| Organ | Cardiovascular System |
| Specimen | Swab, Blood EDTA, Blood Heparin, Semen, Tissue |
| Mode of Inheritance | Autosomal Recessive |
| Also known as | vWD III |
Clinical features
Von Willebrand Disease causes disorders of blood clotting which can lead to symptoms such as easy bruising or bleeding. These dogs are often at risk for excessive bleeding during veterinary procedures.
References
Pubmed ID: 10668811
Year published: 2000
Omia ID: 1058
Omia variant ID:
Turnaround information
- 10 working days