Coat Colour D-Locus (Dilution) – Cat
Kodas: K760
Short description
The melanophilin (MLPH gene) is responsible for the intensity of the coat colour by affecting the distribution of melanin-containing cells.
General information
The melanophilin (MLPH gene) is responsible for the intensity of the coat colour by affecting the distribution of melanin-containing cells. The dilute phenotype in cats is a “dilution” of the expected coal colour. The dilution affects eumelanin and phaeomelanin.
Specifications
| Breeds | All Breeds |
|---|---|
| Gene | MLPH |
| Chromosome | C1 |
| Mutation | c.83delT |
| Organ | Integumentary System |
| Specimen | Swab, Blood EDTA, Blood Heparin, Semen, Tissue |
| Mode of Inheritance | Autosomal Recessive |
| Also known as | D-locus |
Clinical features
Cats expected to be black with the dilute phenotype turn grey (blue). Orange cats turn out cream coloured, Cinnamon dilutes into Fawn, it is described as "coffee and cream" or caramel colour. Chocolate/brown dilutes into lilac, it is described as dove or light taupe gray, and is sometimes called frost or lavender.
References
Pubmed ID: 16860533
Year published: 2006
Omia ID: 31
Omia variant ID:
Turnaround information
- 10 working days