Hereditary Nasal Parakeratosis (HNPK) – Greyhound
Kodas: H460
Short description
Hereditary Nasal Parakeratosis (HNPK) is a skin disorder that causes the formation of crusts and fissures on the nose of affected dogs.
General information
Hereditary Nasal Parakeratosis (HNPK) is a skin disorder that causes the formation of crusts and fissures on the nose of affected dogs. It is caused by a recessive mutation to the gene SUV39H2. The variant analysed in this test occurs in the Greyhound. A closely related variant has also been observed in the Labrador Retriever.
Specifications
| Breeds | |
|---|---|
| Gene | SUV39H2 |
| Chromosome | 2 |
| Mutation | c.996+3_996+6delAAGT |
| Organ | Integumentary System |
| Specimen | Swab, Blood EDTA, Blood Heparin, Semen, Tissue |
| Mode of Inheritance | Autosomal Recessive |
| Also known as | HNPK |
Clinical features
The main symptom of HNPK is the formation of hard, scaly crusts and lesions on the nasal planum (the top edge of the nose).
References
Pubmed ID: 29423952
Year published: 2018
Omia ID: 1373
Omia variant ID:
Turnaround information
- 10 working days