Inflammatory Pulmonary Disease
Kodas: H726
Short description
Recurrent inflammatory pulmonary disease in the Rough Collie is a lung disorder similar to other known forms of Primary Ciliary Dyskinesia (PCD), causing bronchopneumonia in affected dogs.
General information
Recurrent inflammatory pulmonary disease in the Rough Collie is a lung disorder similar to other known forms of Primary Ciliary Dyskinesia (PCD), causing bronchopneumonia in affected dogs. The disease in the Rough Collie is caused by a recessive mutation to the AKNA gene.
Specifications
| Breeds | |
|---|---|
| Gene | AKNA |
| Chromosome | 11 |
| Mutation | c.2717_2720delACAG |
| Organ | Respiratory System |
| Specimen | Swab, Blood EDTA, Blood Heparin, Semen, Tissue |
| Mode of Inheritance | Autosomal Recessive |
| Also known as | IPD |
Clinical features
Symptoms of this disorder start within a few days of birth, and include loud and shallow breathing, coughing, yellowish nasal discharge, fever and foamy vomit. The disease can be effectively treated for a time with antibiotics and secretolytics; however, relapses are likely after treatment ends.
References
Pubmed ID: 31357536
Year published: 2019
Omia ID: 2205
Omia variant ID:
Turnaround information
- 10 working days