Metabolizer of a Cognitive Enhancer
Kodas: H786
Short description
The enzyme CYP1A2 is involved in metabolism; the body’s system for processing chemical compounds.
General information
The enzyme CYP1A2 is involved in metabolism; the body’s system for processing chemical compounds. Research has shown that certain Beagles are affected by a recessive mutation to the CYP1A2 gene, leaving them less able to process certain specific drugs such as the memory-enhancing compound AC-3933.
Specifications
| Breeds | |
|---|---|
| Gene | CYP1A2 |
| Chromosome | 30 |
| Mutation | c.1117C>T |
| Organ | Multiple systems |
| Specimen | Swab, Blood EDTA, Blood Heparin, Semen, Tissue |
| Mode of Inheritance | Autosomal Recessive |
Clinical features
Affected dogs have a decreased functionality of the CYP1A2 enzyme, processing certain drugs differently, but are expected to appear mostly normal and healthy.
References
Pubmed ID: 15564884
Year published: 2004
Omia ID: 1405
Omia variant ID:
Turnaround information
- 10 working days