Factor XI deficiency – Maine Coon
Kodas: K477
Short description
Factor XI (FXI) Deficiency is a disorder that affects blood clotting, which can lead to abnormal, excessive bleeding.
General information
Factor XI (FXI) Deficiency is a disorder that affects blood clotting, which can lead to abnormal, excessive bleeding. The disease is caused by a recessive mutation to the gene F11, and is found in the Maine Coon.
Specifications
| Breeds | |
|---|---|
| Gene | F11 |
| Chromosome | B1 |
| Mutation | c.1546G>A |
| Organ | Cardiovascular System |
| Specimen | Swab, Blood EDTA, Blood Heparin, Semen, Tissue |
| Mode of Inheritance | Autosomal Recessive |
| Also known as | FXI |
Clinical features
Signs of Factor XI Deficiency can include easy bruising, bleeding from the gums, hematomas, and excessive bleeding after injury or surgery.
The severity of the disorder's symptoms can be highly variable., and some affected cats may not show any symptoms at all. As such, the mutation should be seen as causing a risk of abnormal bleeding, rather than a guarantee.
References
Pubmed ID: 35627175
Year published: 2022
Omia ID: 363
Omia variant ID:
Turnaround information
- 10 working days